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Article

Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

Lancet (London, England) - 19 Mar 1994

Ford D, Easton D F, Bishop D T, Narod S A, Goldgar D E

Abstract excerpt

Germline mutations in a gene on chromosome 17q known as BRCA1 are responsible for a large proportion of inherited predispositions to breast and ovarian cancer. In 33 families with evidence of linkage to BRCA1, we estimated the risks of breast and ovarian cancer from the occurrence of second cancers in individuals with breast cancer, and examined the risks of other cancers in BRCA1 carriers. 26 contralateral...

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Source

Identifiers

PMID: 7907678
DOI: 10.1016/s0140-6736(94)91578-4

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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