Article
Detection of the tumour suppressor gene p53 in nasopharyngeal carcinoma in Hong Kong Chinese.
Anticancer research - 1 Jan 2000
Porter M J, Field J K, Lee J C, Leung S F, Lo D, Van Hasselt C A
Abstract excerpt
This study has investigated the expression of the p53 tumour suppressor gene in 41 cases of primary nasopharyngeal carcinomas (NPC) using the p53 monoclonal antibody BP53-12. Moderate p53 expression was found in 54% and strong expression in 12% of the specimens. There was no correlation between p53 expression and any of the clinicopathological parameters or survival. Surprisingly, three research groups have...
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