Article
p53 mutations detected in colorectal carcinoma patients in Hong Kong.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 1997
Leung C S, Cheung M H, Wong C M, Lau K W, Tang C M, Lung M L
Abstract excerpt
A mutational spectrum for exons 5-8 of the p53 tumor suppressor gene in colorectal carcinomas in Hong Kong Chinese was established. Ninety-nine colorectal carcinomas from Hong Kong patients were analyzed for mutations in p53 gene by PCR-single-strand conformation polymorphism analysis and direct...
Topics
- Adult
- Aged
- Asian People
- Colorectal Neoplasms
- CpG Islands
- DNA, Neoplasm
- Exons
- Female
- Genes, p53
- Hong Kong
- Humans
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Sequence Analysis, DNA
- White People