Article
Deregulation of temperature-dependent transcription of the invasion regulatory gene, virB, in Shigella by rho mutation.
Molecular microbiology - 1 Apr 1994
Tobe T, Yoshikawa M, Sasakawa C
Abstract excerpt
Expression of the virB gene, the transcriptional regulator for the invasion genes encoded by the large plasmid of Shigella flexneri, is temperature-regulated. virB transcription is under the control of VirF and H-NS, which act as positive and negative regulators, respectively, and is highly respo...
Topics
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- DNA, Bacterial
- DNA, Superhelical
- DNA-Binding Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Mutagenesis, Insertional
- Nucleic Acid Conformation
- Phenotype
- Rho Factor
- Shigella flexneri
- Temperature
- Trans-Activators
- Transcription Factors
- Transcription, Genetic
- Virulence Factors