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Article

Deregulation of temperature-dependent transcription of the invasion regulatory gene, virB, in Shigella by rho mutation.

Molecular microbiology - 1 Apr 1994

Tobe T, Yoshikawa M, Sasakawa C

Abstract excerpt

Expression of the virB gene, the transcriptional regulator for the invasion genes encoded by the large plasmid of Shigella flexneri, is temperature-regulated. virB transcription is under the control of VirF and H-NS, which act as positive and negative regulators, respectively, and is highly responsive to changes in DNA superhelicity. To further investigate the molecular mechanisms underlying the thermoregulation...

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Identifiers

PMID: 8057851
DOI: 10.1111/j.1365-2958.1994.tb01015.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deregulation of temperature-dependent transcription of the invasion regulatory gene, virB, in Shigella by rho mutation.PMID 8057851Read ↗

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