Article
A Shigella flexneri virulence plasmid encoded factor controls production of outer membrane vesicles.
G3 (Bethesda, Md.) - 5 Nov 2014
Sidik Saima, Kottwitz Haila, Benjamin Jeremy, Ryu Julie, Jarrar Ameer, Garduno Rafael, Rohde John R
Abstract excerpt
Shigella spp. use a repertoire of virulence plasmid-encoded factors to cause shigellosis. These include components of a Type III Secretion Apparatus (T3SA) that is required for invasion of epithelial cells and many genes of unknown function. We constructed an array of 99 deletion mutants comprising all genes encoded by the virulence plasmid (excluding those known to be required for plasmid maintenance) of...
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