Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri.

Journal of bacteriology - 1 Nov 1990

Bernardini M L, Fontaine A, Sansonetti P J

Abstract excerpt

In Shigella flexneri, the ompB locus (containing the ompR and envZ genes) was found to modulate expression of the vir genes, which are responsible for invasion of epithelial cells. vir gene expression was markedly enhanced under conditions of high osmolarity (300 mosM), similar to that encountered in tissues both extra- and intracellularly. Two ompB mutants were constructed and tested for virulence and for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Virulence
Share to Cloning, Molecular
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HeLa Cells

Share to Mutation

Share to Phenotype

Share to Plasmids

Share to Restriction Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 2121709
DOI: 10.1128/jb.172.11.6274-6281.1990
PMCID: PMC526810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri.PMID 2121709Read ↗

OmpC is involved in invasion of epithelial cells by Shigella flexneri.Semantic proximity Read ↗

Characterization of defined ompR mutants of Salmonella typhi: ompR is involved in the regulation of Vi polysaccharide expression.Semantic proximity Read ↗

DNA supercoiling and environmental regulation of virulence gene expression in Shigella flexneri.Semantic proximity Read ↗

A Shigella flexneri virulence plasmid encoded factor controls production of outer membrane vesicles.Semantic proximity Read ↗

Virulence Gene Regulation in <i>Shigella</i>Semantic proximity Read ↗

Identification and characterization of virK, a virulence-associated large plasmid gene essential for intercellular spreading of Shigella flexneri.Semantic proximity Read ↗

Genetic basis of virulence in Shigella species.Semantic proximity Read ↗

The VirSR Two-Component Signal Transduction System Regulates NetB Toxin Production in <i>Clostridium perfringens</i>Semantic proximity Read ↗

Effects of pleiotropic ompR and envZ alleles of Escherichia coli on envelope stress and antibiotic sensitivity.Semantic proximity Read ↗

Molecular analysis of the signaling pathway between EnvZ and OmpR in Escherichia coli.Semantic proximity Read ↗

Genetic basis of virulence in Shigella speciesSemantic proximity Read ↗

Construction and characterisation of a Yersinia enterocolitica O:8 ompR mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.