A chromosome breakage assay to monitor mitotic forces in budding yeast.

doi:10.1242/jcs.107.4.891

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Article

A chromosome breakage assay to monitor mitotic forces in budding yeast.

Journal of cell science - 1 Apr 1994

Brock J A, Bloom K

Abstract excerpt

During the eukaryotic cell cycle, genetic material must be accurately duplicated and faithfully segregated to each daughter cell. Segregation of chromosomes is dependent on the centromere, a region of the chromosome which interacts with mitotic spindle microtubules during cell division. Centromere function in the budding yeast, Saccharomyces cerevisiae, can be regulated by placing an inducible promotor adjacent...

Topics

Base Sequence
Biomechanical Phenomena
Centromere
Chromosomes, Fungal
DNA Damage
DNA, Fungal
DNA-Binding Proteins
Fungal Proteins
Mitosis
Molecular Sequence Data
Mutation
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rad52 DNA Repair and Recombination Protein

Reproduction, Asexual

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Spindle Apparatus

Stress, Mechanical

Source

Open in PubMed

Identifiers

PMID: 8056845
DOI: 10.1242/jcs.107.4.891

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8056845-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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