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Article

The spindle checkpoint: assays for the analysis of spindle checkpoint arrest and recovery.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Fernius Josefin, Hardwick Kevin G

Abstract excerpt

The spindle checkpoint is a surveillance mechanism that ensures the fidelity of chromosome segregation by inhibiting anaphase onset until all chromosomes have established stable bipolar attachments. Here we describe a number of protocols that can be used to assay the ability of budding and fission yeast cells to (1) establish and maintain a spindle checkpoint arrest, and (2) segregate chromosomes efficiently upon...

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PMID: 19475393
DOI: 10.1007/978-1-60327-993-2_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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