Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeast.

doi:10.1083/jcb.133.1.75

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Article

Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeast.

The Journal of cell biology - 1 Apr 1996

Wells W A, Murray A W

Abstract excerpt

The spindle assembly checkpoint is the mechanism or set of mechanisms that prevents cells with defects in chromosome alignment or spindle assembly from passing through mitosis. We have investigated the effects of mini-chromosomes on this checkpoint in budding yeast by performing pedigree analysis...

Topics

Cell Cycle
Centromere
Chromosomes, Fungal
Mitosis
Mutation
Plasmids
Spindle Apparatus
Yeasts

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