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Article

Behavior of dicentric chromosomes in budding yeast.

PLoS genetics - 1 Mar 2021

Cook Diana, Long Sarah, Stanton John, Cusick Patrick, Lawrimore Colleen, Yeh Elaine, Grant Sarah, Bloom Kerry

Abstract excerpt

DNA double-strand breaks arise in vivo when a dicentric chromosome (two centromeres on one chromosome) goes through mitosis with the two centromeres attached to opposite spindle pole bodies. Repair of the DSBs generates phenotypic diversity due to the range of monocentric derivative chromosomes that arise. To explore whether DSBs may be differentially repaired as a function of their spatial position in the...

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Share to Chromosomes, Fungal
Share to DNA Breaks, Double-Stranded

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33735169
DOI: 10.1371/journal.pgen.1009442
PMCID: PMC8009378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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