Article
Association studies of a polymorphism in the Wilms' tumor 1 locus in Norwegian patients with testicular cancer.
International journal of cancer - 15 Aug 1994
Heimdal K R, Lothe R A, Fosså S D, Børresen A L
Abstract excerpt
One strategy for identifying genes involved in genetic predisposition to testicular germ-cell tumors (TC) is to perform association studies with polymorphic loci at or closely linked to candidate genes. Genes involved in normal fetal genital development, such as the Wilms' tumor 1 gene (WT1) located at 11p13, are among such candidates. The present study compares a TC (n = 442) and a control (n = 384) population...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Chromosomes, Human, Pair 11
- Gene Frequency
- Genes, Wilms Tumor
- Humans
- Male
- Middle Aged
- Norway
- Polymorphism, Genetic
