Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WT1 gene analysis in sporadic early-onset and bilateral wilms tumor patients without associated abnormalities.

Journal of pediatric hematology/oncology - 1 Apr 2005

Perotti Daniela, Mondini Patrizia, Terenziani Monica, Spreafico Filippo, Collini Paola, Fossati-Bellani Franca, Radice Paolo

Abstract excerpt

The WT1 gene is responsible for two different genetic conditions characterized by genitourinary anomalies and susceptibility to Wilms tumor (WT): the WAGR syndrome and the Denys-Drash syndrome. Although only rarely, WT1 constitutional mutations have been reported also in WT patients without congenital defects. Due to the high survival rates that characterize the disease, these individuals must be identified and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Infant

Share to Kidney Neoplasms

Share to Loss of Heterozygosity

Share to Wilms Tumor

Share to WT1 Proteins

Source

Identifiers

PMID: 15838390
DOI: 10.1097/01.mph.0000161270.22313.2f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WT1 gene analysis in sporadic early-onset and bilateral wilms tumor patients without associated abnormalities.PMID 15838390Read ↗

Bilateral Wilms tumor and early presentation in pediatric patients is associated with the truncation of the Wilms tumor 1 protein.Semantic proximity Read ↗

Germline WT1 mutations in Wilms' tumor patients: preliminary results.Semantic proximity Read ↗

Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development.Semantic proximity Read ↗

Constitutional and somatic mutations in the WT1 gene in Wilms' tumor patients.Semantic proximity Read ↗

A high incidence of WT1 abnormality in bilateral Wilms tumours in Japan, and the penetrance rates in children with WT1 germline mutation.Semantic proximity Read ↗

Constitutional WT1 mutations in Wilms' tumor patients.Semantic proximity Read ↗

The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q StudySemantic proximity Read ↗

Clinical relevance of mutations in the Wilms tumor suppressor 1 gene WT1 and the cadherin-associated protein beta1 gene CTNNB1 for patients with Wilms tumors: results of long-term surveillance of 71 patients from International Society of Pediatric Oncology Study 9/Society for Pediatric Oncology.Semantic proximity Read ↗

A clinical overview of WT1 gene mutations.Semantic proximity Read ↗

Frequency and heritability of WT1 mutations in nonsyndromic Wilms' tumor patients: a UK Children's Cancer Study Group Study.Semantic proximity Read ↗

WT1, WTX and CTNNB1 mutation analysis in 43 patients with sporadic Wilms' tumor.Semantic proximity Read ↗

The role of WT1 in Wilms tumorigenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.