Article
Germline WT1 mutations in Wilms' tumor patients: preliminary results.
Medical and pediatric oncology - 1 Nov 1996
Li F P, Breslow N E, Morgan J M, Ghahremani M, Miller G A, Grundy P E, Green D M, Diller L R, Pelletier J
Abstract excerpt
We conducted a comparative study of the prevalence of germline WT1 mutations in patients with Wilms' tumor. Patients in Group 1 have familial Wilms' tumor, bilateral disease, associated urogenital anomalies, and/or second cancers. Those in Group 2 are unilateral, sporadic Wilms' patients without other associated conditions. Patients with aniridia or Denys-Drash syndrome are known to have WT1 alterations, and are...
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