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Article

Localisation of susceptibility genes for familial testicular germ cell tumour.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2003

Rapley Elizabeth A, Crockford Gillian P, Easton Douglas F, Stratton Michael R, Bishop D Timothy

Abstract excerpt

Approximately 1700 men in the United Kingdom develop testicular germ cell tumours (TGCT) per year. Among the known risk factors a family history of disease remains one of the strongest (1, 2). Two-percent of TGCT cases report another affected family member. Epidemiological studies have shown that there is an eight to ten fold increase in relative risk of TGCT to brothers of patients and a fourfold increased risk...

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Identifiers

PMID: 12752252
DOI: 10.1034/j.1600-0463.2003.11101171.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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