Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors.

doi:10.3109/07357909309018871

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Article

Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors.

Cancer investigation - 1 Jan 1993

Bruening W, Gros P, Sato T, Stanimir J, Nakamura Y, Housman D, Pelletier J

Abstract excerpt

We have examined the status of the Wilms' tumor suppressor gene (WT1), residing at chromosome 11 band p13, in a total of 40 cancers of the female reproductive tract. Northern blot analysis revealed that the WT1 gene is expressed in a large percentage of ovarian tumors (75%) analyzed. Single-stran...

Topics

Base Sequence
Blotting, Northern
Chromosomes, Human, Pair 11
DNA, Neoplasm
Female
Gene Expression
Genes, Wilms Tumor
Humans
Molecular Sequence Data
Mutation
Ovarian Neoplasms
Polymerase Chain Reaction
Polymorphism, Genetic
RNA, Neoplasm

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