Article
Sequence heterogeneity of HTLV-I proviral DNA in the central nervous system of patients with HTLV-I-associated myelopathy.
Annals of neurology - 1 Aug 1994
Kira J, Koyanagi Y, Yamada T, Itoyama Y, Tateishi J, Akizuki S, Kishikawa M, Baba E, Nakamura M, Suzuki J
Abstract excerpt
The nucleotide sequence of human T-lymphotropic virus type I (HTLV-I) in central nervous system tissue was determined in 3 autopsy cases with HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) and 1 seropositive carrier without HAM/TSP but with multiple sclerosis. All HAM/TSP s...
Topics
- Aged
- Base Sequence
- Central Nervous System Diseases
- DNA, Viral
- Female
- Gene Amplification
- Gene Products, env
- Genes, pX
- Human T-lymphotropic virus 1
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Multiple Sclerosis
- Mutation