Article
Sequence analysis of human T cell lymphotropic virus type I (HTLV-I) Env genes amplified from central nervous system tissues of patients with HTLV-I-associated myelopathy or leukemia.
Microbial pathogenesis - 1 Nov 1995
Maroushek S R, Osame M, Izumo S, Kubota R, Sato E, Bartholomew C, Haase A T
Abstract excerpt
Human T cell lymphotropic virus type I (HTLV-I) is a retrovirus that has been linked to HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP), a chronic or inflammatory neurological disease with some resemblance to multiple sclerosis. We used the polymerase chain reaction to ampli...
Topics
- Adult
- Aged
- Base Sequence
- Brain
- Cloning, Molecular
- Female
- Genes, env
- Human T-lymphotropic virus 1
- Humans
- Leukemia-Lymphoma, Adult T-Cell
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Paraparesis, Tropical Spastic