Article
The transactivator gene of human T-cell leukemia virus type I is more variable within and between healthy carriers than patients with tropical spastic paraparesis.
Journal of virology - 1 Oct 1994
Niewiesk S, Daenke S, Parker C E, Taylor G, Weber J, Nightingale S, Bangham C R
Abstract excerpt
Human T-cell leukemia virus type I (HTLV-1) causes T-cell leukemia and tropical spastic paraparesis (TSP) in a minority of infected people, whereas the majority remain healthy. No association between a particular HTLV-I sequence and disease manifestation has been found in previous studies. We stu...
Topics
- Base Sequence
- Carrier State
- DNA Primers
- DNA, Viral
- Gene Products, tax
- Genes, pX
- Genetic Variation
- Human T-lymphotropic virus 1
- Humans
- Molecular Sequence Data
- Paraparesis, Tropical Spastic
- Polymerase Chain Reaction
- Sequence Homology, Nucleic Acid