Sequence comparisons of HTLV-I from HAM/TSP patients and their asymptomatic spouses.

doi:10.1212/wnl.43.12.2621

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Article

Sequence comparisons of HTLV-I from HAM/TSP patients and their asymptomatic spouses.

Neurology - 1 Dec 1993

Nishimura M, McFarlin D E, Jacobson S

Abstract excerpt

We amplified and sequenced portions of the human T-lymphotropic virus type I (HTLV-I) (U3), pol, env, and pX provirus regions (1212 bp per person) from peripheral blood lymphocytes (PBL) of two married couples (case 1 and case 2). Both husbands are patients with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and the wives are asymptomatic HTLV-I carriers. We selected these regions because...

Topics

Base Sequence
Carrier State
DNA
Epitopes
Female
Genes, pX
HTLV-I Infections
Human T-lymphotropic virus 1
Humans
Male
Marriage
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Paraparesis, Tropical Spastic

Polymerase Chain Reaction

Repetitive Sequences, Nucleic Acid

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 7504797
DOI: 10.1212/wnl.43.12.2621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7504797-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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