Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation.

Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 1994

Aronson B D, Johnson K A, Dunlap J C

Abstract excerpt

The frequency (frq) locus encodes a key component, a state variable, in a cellular oscillator generating circadian rhythmicity. Two transcripts have been mapped to this region, and data presented here are consistent with the existence of a third transcript. Analysis of cDNA clones and clock mutants from this region focuses attention on one transcript encoding a protein. FRQ, which is a central clock component:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to DNA, Complementary

Share to Fungal Proteins

Share to Molecular Sequence Data

Share to Point Mutation

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 8052643
DOI: 10.1073/pnas.91.16.7683
PMCID: PMC44466

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation.PMID 8052643Read ↗

Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms.Semantic proximity Read ↗

Negative feedback defining a circadian clock: autoregulation of the clock gene frequency.Semantic proximity Read ↗

Intergeneric complementation of a circadian rhythmicity defect: phylogenetic conservation of structure and function of the clock gene frequency.Semantic proximity Read ↗

Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock.Semantic proximity Read ↗

Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination.Semantic proximity Read ↗

Domains required for the interaction of the central negative element FRQ with its transcriptional activator WCC within the core circadian clock of Neurospora.Semantic proximity Read ↗

Isoform switching facilitates period control in the Neurospora crassa circadian clock.Semantic proximity Read ↗

Functional significance of FRH in regulating the phosphorylation and stability of Neurospora circadian clock protein FRQ.Semantic proximity Read ↗

Multiple oscillators regulate circadian gene expression in Neurospora.Semantic proximity Read ↗

The genetics of circadian rhythms in Neurospora.Semantic proximity Read ↗

CHD1 remodels chromatin and influences transient DNA methylation at the clock gene frequency.Semantic proximity Read ↗

Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.