Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms.

FEBS letters - 22 Dec 2007

Diernfellner Axel, Colot Hildur V, Dintsis Orfeas, Loros Jennifer J, Dunlap Jay C, Brunner Michael

Abstract excerpt

The large (l) and small (s) isoforms of FREQUENCY (FRQ) are elements of interconnected feedback loops of the Neurospora circadian clock. The expression ratio of l-FRQ vs. s-FRQ is regulated by thermosensitive splicing of an intron containing the initiation codon for l-FRQ. We show that this splicing is dependent on light and temperature and displays a circadian rhythm. Strains expressing only l-FRQ or s-FRQ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Circadian Rhythm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CLOCK Proteins

Share to Fungal Proteins

Share to Neurospora

Share to Protein Isoforms

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 18037381
DOI: 10.1016/j.febslet.2007.11.043
PMCID: PMC2704016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms.PMID 18037381Read ↗

Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation.Semantic proximity Read ↗

Isoform switching facilitates period control in the Neurospora crassa circadian clock.Semantic proximity Read ↗

Negative feedback defining a circadian clock: autoregulation of the clock gene frequency.Semantic proximity Read ↗

Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock.Semantic proximity Read ↗

FRQ-CK1 Interaction Underlies Temperature Compensation of the Neurospora Circadian Clock.Semantic proximity Read ↗

The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock.Semantic proximity Read ↗

The genetics of circadian rhythms in Neurospora.Semantic proximity Read ↗

Multiple oscillators regulate circadian gene expression in Neurospora.Semantic proximity Read ↗

Circadian regulation of the light input pathway in Neurospora crassa.Semantic proximity Read ↗

Functional significance of FRH in regulating the phosphorylation and stability of Neurospora circadian clock protein FRQ.Semantic proximity Read ↗

Temperature-sensitive and circadian oscillators of Neurospora crassa share components.Semantic proximity Read ↗

Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.