Article
Multiple oscillators regulate circadian gene expression in Neurospora.
Proceedings of the National Academy of Sciences of the United States of America - 11 Nov 2003
Correa Alejandro, Lewis Zachary A, Greene Andrew V, March Irene J, Gomer Richard H, Bell-Pedersen Deborah
Abstract excerpt
High-density microarrays were used to profile circadian gene expression in Neurospora crassa cultures grown in constant darkness. We identified 145 clock-controlled genes (ccgs). The ccgs peaked in mRNA accumulation at all phases of the day, with the majority peaking in the late night to early morning. The predicted or known functions of the ccgs demonstrate that the clock contributes to a wide range of cellular...
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