Article
Isoform switching facilitates period control in the Neurospora crassa circadian clock.
Molecular systems biology - 1 Jan 2008
Akman Ozgur E, Locke James C W, Tang Sanyi, Carré Isabelle, Millar Andrew J, Rand David A
Abstract excerpt
A striking and defining feature of circadian clocks is the small variation in period over a physiological range of temperatures. This is referred to as temperature compensation, although recent work has suggested that the variation observed is a specific, adaptive control of period. Moreover, given that many biological rate constants have a Q(10) of around 2, it is remarkable that such clocks remain rhythmic...
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