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Article

Enhanced expression of the multidrug resistance gene in vindesine-resistant human esophageal cancer cells.

Oncology - 1 Jan 2000

Saito T, Hikita M, Kohno K, Tanimura H, Miyahara M, Kobayashi M

Abstract excerpt

We developed and characterized a new series of low- and high-grade multi-drug-resistant (MDR) cell lines of human esophageal carcinoma. Eight vindesine-resistant clones, SH-1-V1, SH-1-V2, SH-1-V3, SH-1-V4, SH-1-V5, SH-1-V6, SH-1-V7, and SH-1-V8 were isolated from the human esophageal cancer cell line, SH-1, by stepwise selection on exposure to increasing doses of vindesine. SH-1-V1 to SH-1-V8 acquired resistance...

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PMID: 8052486
DOI: 10.1159/000227380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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