Enhanced expression of the multidrug resistance gene in vindesine-resistant human esophageal cancer cells.

doi:10.1159/000227380

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Article

Enhanced expression of the multidrug resistance gene in vindesine-resistant human esophageal cancer cells.

Oncology - 1 Jan 2000

Saito T, Hikita M, Kohno K, Tanimura H, Miyahara M, Kobayashi M

Abstract excerpt

We developed and characterized a new series of low- and high-grade multi-drug-resistant (MDR) cell lines of human esophageal carcinoma. Eight vindesine-resistant clones, SH-1-V1, SH-1-V2, SH-1-V3, SH-1-V4, SH-1-V5, SH-1-V6, SH-1-V7, and SH-1-V8 were isolated from the human esophageal cancer cell...

Topics

Alkaloids
Benzylisoquinolines
Drug Resistance
Drug Synergism
Esophageal Neoplasms
Gene Amplification
Humans
Phenotype
RNA, Messenger
Tumor Cells, Cultured
Tumor Stem Cell Assay
Vindesine

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