Increased resistance to cytotoxic agents in ZR75B human breast cancer cells transfected with epidermal growth factor receptor.

doi:10.1016/0303-7207(95)03535-f

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Article

Increased resistance to cytotoxic agents in ZR75B human breast cancer cells transfected with epidermal growth factor receptor.

Molecular and cellular endocrinology - 28 Apr 1995

Dickstein B M, Wosikowski K, Bates S E

Abstract excerpt

Human breast cancer cells selected for multidrug resistance frequently overexpress ligands and receptors in the epidermal growth factor (EGF) receptor family. To determine whether this overexpression contributes to the drug resistant phenotype, EGF receptor transfected ZR75B human breast cancer c...

Topics

Breast Neoplasms
Cisplatin
Doxorubicin
Drug Resistance, Multiple
ErbB Receptors
Fluorouracil
Gene Expression
Humans
Neomycin
Phenotype
RNA, Messenger
Transfection
Tumor Cells, Cultured
Vinblastine

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