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Article

Involvement of V-Ets erythroblastosis virus E26 oncogene homolog 2 in regulation of transcription activity of MDR1 gene.

Acta biochimica et biophysica Sinica - 1 Sept 2012

Wang Jian, Zeng Xiaoqing, Luo Tiancheng, Jin Wei, Chen Shiyao

Abstract excerpt

Over-expression of MDR1 confers multidrug resistance (MDR) in cancers and remains a major cause for the failure of chemotherapy. In the present study, we found that V-Ets erythroblastosis virus E26 oncogene homolog 2 (ETS2) could activate MDR1 transcription and P-glycoprotein (P-gp) expression in...

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Identifiers

PMID: 22819965
DOI: 10.1093/abbs/gms058

Genes

ETS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22819965-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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