Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24.

doi:10.1073/pnas.91.15.6953

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Article

Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jul 1994

Hampton G M, Penny L A, Baergen R N, Larson A, Brewer C, Liao S, Busby-Earle R M, Williams A W, Steel C M, Bird C C

Abstract excerpt

Infection of cervical epithelial cells with so-called "aggressive" subtypes of human papilloma virus (HPV) appears to be an important factor in the etiology of cervical carcinoma. However, mounting evidence suggests that additional genetic changes are required for progression to an invasive carci...

Topics

Alleles
Chromosomes, Human, Pair 11
Female
Gene Deletion
Genes, Tumor Suppressor
Heterozygote
Humans
Polymerase Chain Reaction
Repetitive Sequences, Nucleic Acid
Uterine Cervical Neoplasms

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Identifiers

PMID: 8041728
DOI: 10.1073/pnas.91.15.6953
PMCID: PMC44316

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8041728-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.