Article
Rearrangement of chromosome band 11q13 in HeLa cells.
Anticancer research - 1 Jan 2000
Jesudasan R A, Slovak M L, Sen S, Srivatsan E S
Abstract excerpt
Previous somatic cell genetic and molecular genetic studies have localized the Hela cell tumor suppressor gene to the long arm of chromosome 11. To determine if loss of heterozygosity has occurred for the inactivation of the tumor suppressor gene, we investigated the molecular status of chromosom...
Topics
- Alleles
- Chromosome Banding
- Chromosomes, Human, Pair 11
- DNA Probes
- DNA, Neoplasm
- Gene Rearrangement
- Genetic Markers
- HeLa Cells
- Heterozygote
- Humans
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
