Cervical carcinoma: low frequency of allele loss at loci implicated in other common malignancies.

doi:10.1038/bjc.1993.11

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Article

Cervical carcinoma: low frequency of allele loss at loci implicated in other common malignancies.

British journal of cancer - 1 Jan 1993

Busby-Earle R M, Steel C M, Bird C C

Abstract excerpt

Twenty cervical carcinomas were examined for loss of heterozygosity (LOH) using 22 RFLP markers, which mapped to regions of putative oncosuppressor gene loci, identified as candidates in other common solid tumours. Allele losses were identified in six of the eight chromosomal arms examined, but a...

Topics

Alleles
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human
DNA Probes
DNA, Neoplasm
Female
Genes, Tumor Suppressor
Heterozygote
Humans
Papillomaviridae
Polymorphism, Restriction Fragment Length
Uterine Cervical Neoplasms

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