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Article

Allelic deletion at 11q23.3-q25 is an early event in cervical neoplasia.

Oncogene - 14 May 1998

Evans M F, Koreth J, Bakkenist C J, Herrington C S, McGee J O

Abstract excerpt

Twenty per cent of cervical intraepithelial neoplasias-III (CIN-III) progress to invasive cancer. Human papillomavirus (HPV) infection alone does not determine progression. CIN-III lesions were collected from 161 women. Each tissue was microdissected into a maximum of 32 contiguous units and assayed at multiple microsatellite loci on chromosome 11q, a region frequently deleted in invasive cervical and other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9627121
DOI: 10.1038/sj.onc.1202039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic deletion at 11q23.3-q25 is an early event in cervical neoplasia.PMID 9627121Read ↗

Comparative genomic hybridization detects genetic alterations during early stages of cervical cancer progressionSemantic proximity Read ↗

Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p.Semantic proximity Read ↗

Loss of heterozygosity in cervical carcinoma: subchromosomal localization of a putative tumor-suppressor gene to chromosome 11q22-q24.Semantic proximity Read ↗

Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma.Semantic proximity Read ↗

Cervical intraepithelial neoplasia: prognosis by combined LOH analysis of multiple loci.Semantic proximity Read ↗

Allelic losses at 3p and 11p are detected in both epithelial and stromal components of cervical small-cell neuroendocrine carcinoma.Semantic proximity Read ↗

Loss of heterozygosity at the short arm of chromosome 3 in microdissected cervical intraepithelial neoplasia.Semantic proximity Read ↗

Transition of high‐grade cervical intraepithelial neoplasia to micro‐invasive carcinoma is characterized by integration of HPV 16/18 and numerical chromosome abnormalitiesSemantic proximity Read ↗

Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma.Semantic proximity Read ↗

Allelic imbalance at chromosome region 11q23 in cervical carcinomas.Semantic proximity Read ↗

Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix.Semantic proximity Read ↗

Allelotyping of all chromosomal arms in invasive cervical cancer.Semantic proximity Read ↗

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