Article
Identification of a 6-cM minimal deletion at 11q23.1-23.2 and exclusion of PPP2R1B gene as a deletion target in cervical cancer.
Cancer research - 1 Dec 2000
Pulido H A, Fakruddin M J, Chatterjee A, Esplin E D, Beleño N, Martinez G, Posso H, Evans G A, Murty V V
Abstract excerpt
Previous functional and deletion mapping studies on cervical cancer (CC) have implicated one or more tumor suppressor genes (TSGs) on chromosome 11 at q13 and q22-24 regions. Of these, the 11q22-24 region exhibits frequent allelic deletions in a variety of solid tumor types, suggesting the presence of critical genes for tumor suppression in this region. However, the precise region of deletion on 11q is not...
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