Article
Allelotyping of all chromosomal arms in invasive cervical cancer.
Oncogene - 19 Dec 1996
Rader J S, Kamarasova T, Huettner P C, Li L, Li Y, Gerhard D S
Abstract excerpt
The best characterized factor in the development of cervical cancer is the integration, of human papillomavirus into cervical cell chromosomes. In addition to HPV integration, the neoplastic process probably requires the activation of cellular protooncogenes and loss of tumor suppressor gene function. Loss of heterozygosity analysis in a large sample is used to identify regions which harbor putative tumor...
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