Article
Absence of N-ras mutations in myeloid and lymphoid blast crisis of chronic myeloid leukemia.
Cancer research - 15 Jul 1994
Watzinger F, Gaiger A, Karlic H, Becher R, Pillwein K, Lion T
Abstract excerpt
Mutations within N-ras oncogene codons 12, 13, and 61 occur in approximately 25-30% of patients with acute nonlymphocytic leukemia and at a lower frequency (6-20%) in patients with acute lymphocytic leukemia. Moreover, N-ras mutations have been described in patients with chronic myeloid leukemia...
Topics
- Base Sequence
- Blast Crisis
- Genes, ras
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Molecular Sequence Data
- Mutation