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Article

Mutations of the myeloid transcription factor CEBPA are not associated with the blast crisis of chronic myeloid leukaemia.

British journal of haematology - 1 May 2006

Pabst Thomas, Stillner Erica, Neuberg Donna, Nimer Stephen, Willman Cheryl L, List Alan F, Melo Junia V, Tenen Daniel G, Mueller Beatrice U

Abstract excerpt

The transcription factor CEBPA is crucial for normal myeloid differentiation. CEBPA gene mutations have been reported in patients with acute myeloid leukaemia. The inevitable evolution of chronic myeloid leukaemia (CML) in chronic phase (CP) to a fatal blast crisis (BC) is assumed to result from the acquisition of additional genetic changes in the leukaemic clone. Gain of CEBPA mutations might represent a key...

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Identifiers

PMID: 16643447
DOI: 10.1111/j.1365-2141.2006.06057.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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