Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication of a Moloney murine leukemia virus mutant lacking the ELP binding site.

Virology - 15 Aug 1994

Coulombe J, Dubé M, Gray D A

Abstract excerpt

A mutant Moloney murine leukemia virus was created in which the binding site for the embryonal long terminal repeat binding protein had been replaced with a synthetic linker sequence. The virus was found to replicate normally in murine 3T3 fibroblasts, and the mutation was stably transmitted throughout repeated passages. The binding site is therefore dispensable with respect to viral replication. Titers of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Binding Sites
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Transcription Factors

Source

Identifiers

PMID: 8030273
DOI: 10.1006/viro.1994.1468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication of a Moloney murine leukemia virus mutant lacking the ELP binding site.PMID 8030273Read ↗

Expression of a truncated retroviral envelope gene enhances expression of normal cellular phenotypes.Semantic proximity Read ↗

Mutations that abrogate transactivational activity of the feline leukemia virus long terminal repeat do not affect virus replication.Semantic proximity Read ↗

ORF30 and ORF34 are essential for expression of late genes in murine gammaherpesvirus 68.Semantic proximity Read ↗

Role of the LTR region between the enhancer and promoter in mink cell focus-forming murine leukemia virus pathogenesis.Semantic proximity Read ↗

Forced lytic replication impairs host colonization by a latency-deficient mutant of murine gammaherpesvirus-68.Semantic proximity Read ↗

A single point mutation activates the Moloney murine leukemia virus long terminal repeat in embryonal stem cells.Semantic proximity Read ↗

Evidence for a stem cell-specific repressor of Moloney murine leukemia virus expression in embryonal carcinoma cells.Semantic proximity Read ↗

Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity.Semantic proximity Read ↗

Mutations affecting the cytoplasmic domain of the Moloney murine leukemia virus envelope protein: rapid reversion during replication.Semantic proximity Read ↗

Comprehensive mutational analysis of the Moloney murine leukemia virus envelope protein.Semantic proximity Read ↗

Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity.Semantic proximity Read ↗

Mutational analysis of bovine leukemia virus Rex: identification of a dominant-negative inhibitor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.