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Article

Bovine papillomavirus E2 repressor mutant displays a high-copy-number phenotype and enhanced transforming activity.

Journal of virology - 1 Feb 1990

Riese D J, Settleman J, Neary K, DiMaio D

Abstract excerpt

The methionine codon at bovine papillomavirus type 1 nucleotide 3091 was mutated to determine whether it may serve as an initiation codon for an E2 transcriptional repressor protein and to determine the role of the repressor in the biological activities of the virus. A series of transient expression experiments with CV1 cells documented that the mutation reduced expression of repressor activity from the viral...

Topics

Animals
Bovine papillomavirus 1
Cell Line
Cell Transformation, Neoplastic
DNA, Viral
Genes, Regulator
Genes, Viral
Mutation
Oligonucleotide Probes
Papillomaviridae
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcriptional Activation

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Open in PubMed Open full text

Identifiers

PMID: 2153255
DOI: 10.1128/JVI.64.2.944-949.1990
PMCID: PMC249196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2153255-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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