Article
Mutations affecting the cytoplasmic domain of the Moloney murine leukemia virus envelope protein: rapid reversion during replication.
Virus research - 1 Mar 1996
Granowitz C, Berkowitz R D, Goff S P
Abstract excerpt
Five premature termination mutations and five missense mutations were introduced into the portion of cloned Moloney murine leukemia virus (M-MuLV) DNA encoding the Env cytoplasmic domain. All of the mutant DNAs gave rise to replication-competent virus after transfection of NIH/3T3 cells, but seve...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cell Line
- Cell Line, Transformed
- Chlorocebus aethiops
- Cloning, Molecular
- Cytoplasm
- DNA, Viral
- Mice
- Molecular Sequence Data
- Moloney murine leukemia virus
- Mutation
- Rats
- Transfection
- Viral Envelope Proteins