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Article

Evidence for a stem cell-specific repressor of Moloney murine leukemia virus expression in embryonal carcinoma cells.

Molecular and cellular biology - 1 Aug 1990

Loh T P, Sievert L L, Scott R W

Abstract excerpt

A negative regulatory element (NRE) spanning the tRNA primer-binding site (PBS) of Moloney murine leukemia virus (M-MuLV) mediates repression of M-MuLV expression specifically in embryonal carcinoma (EC) cells. We precisely defined the element by base-pair mutagenesis to an 18-base-pair segment o...

Topics

Animals
Base Sequence
Cell Line
Exodeoxyribonucleases
Gene Expression Regulation
Genes, Regulator
Molecular Sequence Data
Moloney murine leukemia virus
Mutation
Oligonucleotide Probes
RNA, Transfer
Repetitive Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Restriction Mapping

Teratoma

Transfection

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Identifiers

PMID: 2370861
DOI: 10.1128/mcb.10.8.4045-4057.1990
PMCID: PMC360915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2370861-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Evidence for a stem cell-specific repressor of Moloney murine leukemia virus expression in embryonal carcinoma cells.PMID 2370861Read ↗

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