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Article

ORF30 and ORF34 are essential for expression of late genes in murine gammaherpesvirus 68.

Journal of virology - 1 Mar 2009

Wu Ting-Ting, Park Tina, Kim Hana, Tran Thuy, Tong Leming, Martinez-Guzman DeeAnn, Reyes Nichole, Deng Hongyu, Sun Ren

Abstract excerpt

A hallmark of productive infection by DNA viruses is the coupling of viral late gene expression to genome replication. Here we report the identification of open reading frame 30 (ORF30) and ORF34 as viral trans factors crucial for activating late gene transcription following viral DNA replication during lytic infection of murine gammaherpesvirus 68 (MHV-68). The mutant virus lacking either ORF30 or ORF34...

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Source

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Identifiers

PMID: 19091863
DOI: 10.1128/JVI.01785-08
PMCID: PMC2643722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ORF30 and ORF34 are essential for expression of late genes in murine gammaherpesvirus 68.PMID 19091863Read ↗

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