Article
Role of the LTR region between the enhancer and promoter in mink cell focus-forming murine leukemia virus pathogenesis.
Virology - 25 Apr 2001
Yoshimura F K, Wang T
Abstract excerpt
Long terminal repeat (LTR) sequences are important determinants of mink cell focus-forming (MCF) murine leukemia virus pathogenesis. These sequences include the enhancer and sequences between the enhancer and promoter (DEN). In a previous study we showed that a virus missing the DEN region in its LTR was severely attenuated in its ability to induce thymic lymphoma. In this study we observed that a virus with an...
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