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Article

Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase.

Development (Cambridge, England) - 1 May 1993

Melnick M B, Perkins L A, Lee M, Ambrosio L, Perrimon N

Abstract excerpt

Formation of the tail region of the Drosophila larva requires the activities of the terminal class genes. Genetic and molecular analyses of these genes suggests that localized activation of the receptor tyrosine kinase torso at the posterior egg pole triggers a signal transduction pathway. This pathway, mediated through the serine/threonine protein kinase D-raf and the protein tyrosine phosphatase corkscrew,...

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Identifiers

PMID: 8375330
DOI: 10.1242/dev.118.1.127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase.PMID 8375330Read ↗

Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK.Semantic proximity Read ↗

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