Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells.

doi:10.1093/carcin/15.12.2781

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Article

Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells.

Carcinogenesis - 1 Dec 1994

Kloth M T, Gee R L, Messing E M, Swaminathan S

Abstract excerpt

To determine which of the N-acetyltransferase (NAT) alleles [monomorphic (NAT1) or polymorphic (NAT2)] are expressed in the target cells for arylamine carcinogenesis, namely normal human uroepithelial cells, cDNA was prepared from cellular RNA and amplified by polymerase chain reaction (PCR), usi...

Topics

Acetylation
Adult
Alleles
Amines
Arylamine N-Acetyltransferase
Biomarkers
Caffeine
Cells, Cultured
Cytochrome P-450 CYP1A2
Cytochrome P-450 Enzyme System
DNA, Complementary
Epithelial Cells
Epithelium
Female
Gene Expression
Genetic Predisposition to Disease
Humans
Male

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