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Article

Gene disruption/knock-in analysis of mONT3: vector construction by employing both in vivo and in vitro recombinations.

The International journal of developmental biology - 1 Jan 2005

Ikeya Makoto, Kawada Masako, Nakazawa Yoko, Sakuragi Makoto, Sasai Noriaki, Ueno Morio, Kiyonari Hiroshi, Nakao Kazuki, Sasai Yoshiki

Abstract excerpt

We report the isolation, spatial/temporal expression and gene disruption phenotype of the mouse ONT3 (mONT3) gene, which encodes a novel secreted signaling protein belonging to the Olfactomedin/Noelin/Tiarin family. During early embryogenesis, mONT3 is detected in the proximal region of the allantois on embryonic day (E) 7.25, in the lateral plate mesoderm on E 8.0 and in the CNS and heart on E 8.5. The...

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PMID: 16172977
DOI: 10.1387/ijdb.051975mi

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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