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Article

Novel point mutation in exon 10 of the RET proto-oncogene in a family with medullary thyroid carcinoma.

American journal of medical genetics - 7 Jul 1998

Oriola J, Páramo C, Halperin I, García-Mayor R V, Rivera-Fillat F

Abstract excerpt

Medullary thyroid carcinoma (MTC) may occur sporadically or as part of the autosomal dominant multiple endocrine neoplasia type 2 (MEN 2). Three hereditary forms of MEN 2 have been identified: MEN 2A, MEN 2B, and familial MTC (FMTC). Missense germ-line mutations in the RET proto-oncogene have been identified as cause of these endocrine diseases. Mutations are found in exons 10 and 11 in MEN 2A and FMTC families...

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Source

Identifiers

PMID: 9677065
DOI: 10.1002/(sici)1096-8628(19980707)78:3<271::aid-ajmg13>3.0.co;2-c

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Novel point mutation in exon 10 of the RET proto-oncogene in a family with medullary thyroid carcinoma.PMID 9677065Read ↗

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Three novel mutations in the RET proto-oncogene.Semantic proximity Read ↗

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A newly detected mutation of the RET protooncogene in exon 8 as a cause of multiple endocrine neoplasia type 2A.Semantic proximity Read ↗

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