RET proto-oncogene mutations in French MEN 2A and FMTC families.

doi:10.1093/hmg/3.11.1939

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Article

RET proto-oncogene mutations in French MEN 2A and FMTC families.

Human molecular genetics - 1 Nov 1994

Schuffenecker I, Billaud M, Calender A, Chambe B, Ginet N, Calmettes C, Modigliani E, Lenoir G M

Abstract excerpt

Constitutional mutations of the RET proto-oncogene have been identified in multiple endocrine neoplasia type 2A (MEN 2A), type 2B (MEN 2B) and familial medullary thyroid carcinoma (FMTC) families. We sequenced RET exons 10 and 11 in 86 unrelated patients with an inherited predisposition to MTC (e...

Topics

Carcinoma, Medullary
DNA Mutational Analysis
DNA, Neoplasm
Drosophila Proteins
France
Humans
Multiple Endocrine Neoplasia Type 2a
Mutation
Phenotype
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases
Thyroid Neoplasms

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Open in PubMed

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PMID: 7874109
DOI: 10.1093/hmg/3.11.1939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7874109-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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