Article
[Current studies on the identification of susceptibility genes for IDDM in NOD mice].
Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1994
Miyazaki J, Ishii M, Tashiro F
Abstract excerpt
Until recently, localization of genes involved in multifactorial diseases, such as diabetes, was thought to be impracticable. The recent development of microsatellite genetic markers detected by PCR has facilitated detailed genetic analysis of complex traits. Microsatellite markers have been utilized for genetic analysis of NOD mice which spontaneously develop autoimmune IDDM similar to the human disease. There...
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