Article
Characterizations of candidate genes for IDD susceptibility from the diabetes-prone NOD mouse strain.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1993
Chesnut K, She J X, Cheng I, Muralidharan K, Wakeland E K
Abstract excerpt
The nucleotide sequences of the NOD and C57BL/6J alleles of Glut-2, Sod-2, and Il-2 were determined by RT-PCR sequencing. Each of these loci is located in intervals that strongly correlated with susceptibility to diabetes in an (NOD/Uf x C57BL/6J)F1 x NOD/Uf backcross. No significant variations in the alleles of Glut-2 at 16 cM on Chromosome (Chr) 3 or Sod-2 at 8 cM on Chr 17 were detected. However, the Il-2...
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