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Article

Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation.

1 Mar 1998

Abstract excerpt

Genetic susceptibility to type 1 diabetes in the nonobese diabetic (NOD) mouse involves at least 17 Idd loci. Idd1 has been mapped to a class II gene in the major histocompatibility complex (MHC), whereas the products and functions of the remaining Idd loci are unresolved. To investigate how non-MHC Idd genes regulate islet inflammation and IDDM progression, NOD mice were compared with the nonobese...

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Identifiers

PMID: 9519736
DOI: 10.2337/diabetes.47.3.331

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Independent genetic regulation of T-cell and antigen-presenting cell participation in autoimmune islet inflammation.PMID 9519736Read ↗

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