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Article

Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: an approach for the genetic dissection of complex traits.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 1996

Yui M A, Muralidharan K, Moreno-Altamirano B, Perrin G, Chestnut K, Wakeland E K

Abstract excerpt

Insulin-dependent (Type 1) diabetes (IDD) in the NOD mouse is inherited as a complex polygenic trait making the identification of susceptibility genes difficult. Currently none of the non-MHC IDD susceptibility genes in NOD have been identified. In this paper we describe the congenic mouse approa...

Topics

Animals
Chromosome Mapping
Crosses, Genetic
Diabetes Mellitus, Type 1
Disease Models, Animal
Disease Susceptibility
Female
Male
Mice
Mice, Inbred C57BL
Mice, Inbred NOD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancreas

Phenotype

Source

Identifiers

PMID: 8661724
DOI: 10.1007/s003359900097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8661724-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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