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Article

Comparative genetics: synergizing human and NOD mouse studies for identifying genetic causation of type 1 diabetes.

The review of diabetic studies : RDS - 1 Jan 2012

Driver John P, Chen Yi-Guang, Mathews Clayton E

Abstract excerpt

Although once widely anticipated to unlock how human type 1 diabetes (T1D) develops, extensive study of the nonobese diabetic (NOD) mouse has failed to yield effective treatments for patients with the disease. This has led many to question the usefulness of this animal model. While criticism about the differences between NOD and human T1D is legitimate, in many cases disease in both species results from...

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Share to Diabetes and associated disorders
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Genetic Predisposition to Disease

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Share to Mice, Inbred NOD

Share to Pancreatic function and diabetes

Source

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Identifiers

PMID: 23804259
DOI: 10.1900/RDS.2012.9.169
PMCID: PMC3740689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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